Cédric Deluz

The paper investigates the distinct roles of SRCAP and H2A.Z in gene regulation during the cell cycle in pluripotent stem cells, revealing SRCAP's H2A.Z-independent inhibitory function and H2A.Z's repressive role in lineage-specific gene expression.

This study investigates how charge, hydrophobicity, and cooperativity affect the target search of SOX2 and ESRRB transcription factors using single-molecule imaging and genomic analysis.

The paper investigates how protein synthesis and decay rates are coordinated in mammalian cells, revealing passive and mTOR-dependent mechanisms that maintain proteome stability.

The paper investigates how fluctuations in OCT4, SOX2, and NANOG concentrations affect their genomic binding in mouse embryonic stem cells, revealing distinct concentration-dependent behaviors.

This study investigates how pluripotent stem cells reactivate gene expression and rebind transcription factors during mitotic exit using a novel temporal separation method.

This study investigates how OCT4 and SOX2 regulate chromatin accessibility in mouse embryonic stem cells across the cell cycle, showing their independent and cooperative roles in maintaining pluripotency.

The paper shows that fluctuations in OCT4 and SOX2 levels influence cell fate decisions by affecting chromatin accessibility at differentiation enhancers.

The paper shows that mitotic chromosome binding of transcription factors correlates with their interphase properties and impact on chromatin accessibility.