Brief report on the development of patient-derived lung cancer organoids with keratinizing squamous cell carcinoma morphology
Eabha O'Sullivan, Christina Cahill, Rebecca M. O'Brien, Ismail Suliman Elgenaidi, Gavin McManus, William Mc Cormack, Sinead M. Hurley, Laura Staunton, Siobhan A. Nicholson, Stephen P. Finn, Ronan J. Ryan, Gerard J. Fitzmaurice, Maeve Aine Lowery, Jacintha N O'Sullivan, Kathy A. Gately
This paper develops patient-derived lung cancer organoids that replicate histological features of keratinizing squamous cell carcinoma, offering a tool for studying tumor biology and drug testing.
bioRxiv · Apr 10, 2026 · PreprintCancer Biology