Developmental BiologyBiochemical JournalPeer-reviewed
An ERK5-KLF2 signalling module regulates early embryonic gene expression dynamics and stem cell rejuvenation
Helen A. Brown, Charles A.C. Williams, Houjiang Zhou…·Greg M. Findlay
This study identifies an ERK5-KLF2 signalling module that regulates 2C gene expression and mESC rejuvenation through both transcriptional activation and phosphorylation-induced degradation of KLF2.
13 citations