Houjiang Zhou

The paper identifies SRPK-mediated phosphorylation of MAP1S, showing it regulates proteolytic processing and microtubule binding during neurodevelopment.

The paper identifies ERK5's role in regulating Annexin A2/S100A10 complex and membrane dynamics in mESCs through transcriptional induction of KLF2.

The paper shows that Zuo1, an Hsp40 cochaperone, is required for translational control and proteostasis maintenance in yeast under TORC1 inhibition.

This study identifies an ERK5-KLF2 signalling module that regulates 2C gene expression and mESC rejuvenation through both transcriptional activation and phosphorylation-induced degradation of KLF2.

This paper demonstrates the degradation of endogenous K-RAS and H-RAS using an AdPROM system, offering a new approach for targeting undruggable cancer proteins.