The "replacing surgery" of cpDNA: de novo chemical synthesis and in vivo functional testing of Chlamydomonas chloroplast genome
Chunli Guo, Guiying Zhang, Hui Wang, Rui Mei, Xinyi Li, Hui Li, Bin Jia, Chaogang Wang, Zhangli Hu
The paper synthesizes and functionally tests an artificial chloroplast genome in Chlamydomonas reinhardtii, demonstrating its ability to replace the native genome and perform normal photosynthesis.
bioRxiv · Jan 5, 2023 · PreprintMolecular Biology