Bona fide hematopoietic stem cells in zebrafish originate from the supra-intestinal artery
Shachuan Feng, Rui Qu, Yingzhu He, Tingting Huang, Youqi Wang, Thi Huong Trinh, Kefan Cheng, Shizheng Zhao, Ying Kao Huang, Hao Zhu, Sicong He, Zilong Wen
This study shows that in zebrafish, hematopoietic stem cells (HSCs) originate from the supra-intestinal artery, not the dorsal aorta, as previously thought.
bioRxiv · May 20, 2025 · PreprintDevelopmental Biology