Protective Effect of Cannabinoid Type II Receptor Ligand on Bleomycin-Induced Pulmonary Fibrosis in Mice
Cheng Cao, Run-Lin Wang, Chen-xin Guo, Xiaowei Xu, Jia-hui Wei, Wenzhuo Cheng, Yi-zhe Yu, Jia-jie Shi, Zhi-wei Feng, Yan Chen
This study evaluates the protective effects of COCA, a CB2R ligand identified via AI-driven virtual screening, against BLM-induced pulmonary fibrosis in mice, showing reduced inflammation and fibrosis.
PLoS ONE · Feb 27, 2026Peer-reviewedPharmacology & Toxicology