The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential
Robert M. Morabito, David Tatarakis, Ryan Swick, Samantha Stettnisch, Pavan K. Nayak, Thomas Friedrich Schilling, Julia A. Horsfield, Benjamin L. Martin
The paper identifies a Wnt signaling to Sox2 ratio that predicts neuromesodermal fate potential in zebrafish and shows Sox2's role in maintaining progenitor states.
Development · Oct 10, 2025Peer-reviewedDevelopmental Biology