Constructing and visualizing cancer genomic maps in 3D spatial context by phenotype-based high-throughput laser-aided isolation and sequencing (PHLI-seq)
Sungsik Kim, Amos Chungwon Lee, Han‐Byoel Lee, Jinhyun Kim, Yushin Jung, Han Suk Ryu, Yong‐Ju Lee, Sangwook Bae, Minju Lee, Kyungmin Lee, Ryong Nam Kim, Woong‐Yang Park, Wonshik Han, Sunghoon Kwon
This paper introduces PHLI-seq, a method to isolate and sequence cancer cells in 3D space, revealing genomic heterogeneity and linking genotypes to phenotypes in breast cancer.
Genome biology · Oct 8, 2018Peer-reviewedGenomics