Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility
E. Eck, J. Liu, M. Kazemzadeh-Atoufi, S. Ghoreishi, S. A. Blythe, H. Garcia
The paper tests thermodynamic models of gene regulation in Drosophila embryos and finds that transcription factor-driven chromatin accessibility better explains hunchback transcription dynamics than existing models.
bioRxiv · Jan 27, 2020Biophysics