Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1
C. J. Mycroft-West, S. Abdelkarim, H. M. E. Duyvesteyn, N. S. Gandhi, M. A. Skidmore, R. J. Owens, L. Wu
This study determines the structure of NDST1, revealing its catalytic domains and a non-catalytic N-terminal domain, and proposes a mechanism for its function.
bioRxiv · Aug 30, 2023Biochemistry