Author

N. S. Gandhi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

C. J. Mycroft-West· 2 shared M. A. Skidmore· 2 shared A. A. Khromykh· 1 shared A. Amarilla· 1 shared A. Suhrbier· 1 shared C. M. Spalluto· 1 shared D. J. J. Sng· 1 shared D. Su· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

C. J. Mycroft-West

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2 papers

Recent·Most cited

BiochemistrybioRxivAug 30, 2023

Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1

C. J. Mycroft-West, S. Abdelkarim, H. M. E. Duyvesteyn…·L. Wu

This study determines the structure of NDST1, revealing its catalytic domains and a non-catalytic N-terminal domain, and proposes a mechanism for its function.

DOI 10.1038/s41467-024-45419-4

humanstructural biology

𝕏 PostBluesky

MicrobiologybioRxivJun 24, 2020

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi…·J. E. Turnbull

This paper shows that pixatimod inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction, demonstrating its potential as an anti-COVID-19 therapeutic.

DOI 10.1021/acscentsci.1c01293

humanmouse

𝕏 PostBluesky