Author

S. Akle

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Evolutionary Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alzheimer's Disease Neuroimaging Initiative· 1 shared D. J. Balick· 1 shared D. W. Radke· 1 shared J. H. Sul· 1 shared R. C. Green· 1 shared S. R. Sunyaev· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperEvolutionary Biology

Alzheimer's Disease Neuroimaging Initiative

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1 paper

Recent·Most cited

Purifying selection on noncoding deletions of human regulatory elements detected using their cellular pleiotropy

D. W. Radke, J. H. Sul, D. J. Balick, S. Akle, Alzheimer's Disease Neuroimaging Initiative, R. C. Green, S. R. Sunyaev

The paper uses genomic deletions to assess purifying selection on noncoding regulatory elements, finding preservation of DHS and enhancer sites but not transcribed or heterochromatin regions.

bioRxiv · May 19, 2020Evolutionary Biology