Cancer BiologybioRxivPreprint
FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma unveil a necessary role for Erk signaling
G. Cristinziano, M. Porru, D. Lamberti…·O. Segatto
This paper develops FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma and shows that Erk signaling is essential for tumor growth, with double blockade of FF-Ras-Erk pathways improving therapeutic efficacy.
DOI 10.1101/2020.05.20.106104