S. Aris-Brosou

Viral spillover risk increases with climate change in High Arctic lake sediments

The paper quantifies viral spillover risk in High Arctic lake sediments, showing it increases with glacier melt runoff and is higher than in soil.

Viral evolutionary dynamics predict Influenza-Like-Illnesses in patients

This study links viral evolutionary dynamics to Influenza-Like-Illness (ILI) progression, showing predictive power based on genetic data collected weeks before ILI peaks.

Climate change negatively impacts dominant microbes in the sediments of a High Arctic lake

The paper examines how increased runoff, as a proxy for climate change, affects microbial community structure and functional diversity in Arctic lake sediments.

Microbial genomes retrieved from High Arctic lake sediments encode for adaptation to cold and oligotrophic environments

The paper analyzes microbial genomes from High Arctic lake sediments to identify adaptations to cold and oligotrophic conditions.

Direct evidence of an increasing mutational load in humans

The paper analyzes genome data from 2,062 individuals, including ancient humans, to show that risk alleles for diseases like asthma and diabetes have increased in frequency over 45,000 years in Europe, while deleterious homozygosity has decreased.

Viral long-term evolutionary strategies favor stability over proliferation

This study examines viral evolution, showing that stability-related genes are under both episodic diversifying selection and correlated evolution, favoring stability over proliferation.

How the Central American Seaway and an ancient northern passage affected flatfish diversification

The paper uses molecular data and relaxed clocks to show flatfish diversified in two phases linked to the closure of the Central American Seaway and a northern dispersal route.

Widespread Historical Contingency in Influenza Viruses

This paper introduces a statistical method to detect epistasis in influenza A virus genomes, finding widespread historical contingency through correlated evolution across distant sites.

Viral outbreaks involve destabilized evolutionary networks: evidence from Ebola, Influenza and Zika

The paper analyzes genomic data from Ebola, Influenza, and Zika outbreaks to show that outbreak viruses exhibit destabilized evolutionary networks compared to non-outbreak viruses.