Short- and Long-Term Effects of Social Isolation on Adult Murine Bone are Sex-Dependent
William Aidan Martel, S. Bradley King, Eleanor Buchanan, Brooklynn M Merrill, Julia Patrizia Stohn, Daniel J. Brooks, Deborah J. Barlow, Katherine J. Motyl, Rebecca V. Mountain
This study shows that social isolation reduces bone parameters in male mice but not females, with effects appearing rapidly in males and some changes in females after short-term isolation.
Biology of Sex Differences · Sep 26, 2026Peer-reviewedPhysiology