Fruit bromelain derived peptides destabilize growth of amyloidal fibrils
S. Das, S. Dutta, R. K. Paidi, S. C. Biswas, U. C. Halder, D. Bhattacharyya
The paper shows that bromelain peptides from pineapple inhibit Aβ fibrillation and dissociate preformed fibrils, reducing their cytotoxicity in cells and animal models.
bioRxiv · Apr 20, 2020 · PreprintBiochemistry