S. Dakshanamurthy

SARS-CoV-2 Omicron (BA.1 and BA.2) specific novel CD8+ and CD4+ T cell epitopes targeting spike protein.

This study identifies CD8+ and CD4+ T cell epitopes specific to SARS-CoV-2 Omicron variants, targeting spike protein mutations, with high population coverage and potential for improved vaccine efficacy.

Design of Peptide Vaccine for COVID19: CD8+ and CD4+ T cell epitopes from SARS-CoV-2 open-reading-frame protein variants

This study identifies CD8+ and CD4+ T cell epitopes from SARS-CoV-2 proteins that are immunogenic and protective across multiple variants, offering potential for peptide vaccine design.

Design of T cell epitope-based vaccine candidate for SARS-CoV-2 targeting spike and nucleocapsid protein escape variants

This study predicts T cell epitopes for SARS-CoV-2 spike and nucleocapsid proteins using immunoinformatics tools and validates them for use in epitope-based vaccines against current variants and variants of concern.

Scaffold Protein RACK1 inhibitor compounds prevent the Focal Adhesion Kinase mediated breast cancer cell migration and invasion potential

The paper shows RACK1 inhibitors reduce breast cancer cell migration and invasion by blocking FAK activation, suggesting a potential therapeutic strategy for preventing metastasis.

Predicting Environmental Chemical Carcinogenicity using a Hybrid Machine-Learning Approach

This study develops hybrid machine learning models to predict environmental chemical carcinogenicity, achieving comparable performance to existing models across multiple tasks.

Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism