Author

S. E. Darch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. K. Lindon· 1 shared C. Beloin· 1 shared J. Gibbons· 1 shared J.-M. Ghigo· 1 shared K. Dominguez· 1 shared L. Touqui· 1 shared M. Whiteley· 1 shared S. Letoffe· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. K. Lindon

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2 papers

Recent·Most cited

Group B Streptococcus drives major transcriptomic changes in the colonic epithelium.

K. Dominguez, A. K. Lindon, J. Gibbons, S. E. Darch, T. M. Randis

This study shows that Group B Streptococcus's βH/C toxin drives transcriptomic changes in the colonic epithelium, facilitating extraintestinal dissemination in a mouse model.

bioRxiv · Jan 24, 2023 · PreprintMicrobiology

Volatile hydrogen cyanide released by Pseudomonas aeruginosa provides a competitive advantage over Staphylococcus aureus in biofilm and in vivo lung environments

S. Letoffe, Y. Wu, S. E. Darch, C. Beloin, M. Whiteley, L. Touqui, J.-M. Ghigo

This study shows that Pseudomonas aeruginosa releases volatile hydrogen cyanide (HCN) that inhibits Staphylococcus aureus growth in low oxygen environments, providing a competitive advantage in biofilms and in vivo lung infections.

bioRxiv · Mar 24, 2022 · PreprintMicrobiology