Cancer cell sedimentation in 3D cultures reveals active migration regulated by self-generated gradients and adhesion sites
N. M. Dimitriou, S. Flores-Torres, M. Kyriakidou, J. M. Kinsella, G. D. Mitsis
The paper investigates cancer cell sedimentation in 3D cultures, showing active migration driven by self-generated gradients and adhesion sites, confirmed by mathematical modeling and drug inhibition experiments.
bioRxiv · Feb 15, 2023Bioengineering