Author

S. H. Sikaroodi

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Evolutionary Biology· 1

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Organism:E. coli· 1 Approach:experimental assay· 1

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B. Kacar· 1 shared R. Monasky· 1 shared S. Kryazhimskiy· 1 shared S. Venkataram· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperEvolutionary Biology

B. Kacar

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1 paper

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Evolutionary BiologybioRxivMay 31, 2020

Evolutionary Stalling and a Limit on the Power of Natural Selection to Improve a Cellular Module

S. Venkataram, R. Monasky, S. H. Sikaroodi…·B. Kacar

This study shows that natural selection can stall in improving a cellular module, the translation machinery, due to epistasis and depletion of beneficial mutations in E. coli.

DOI 10.1073/pnas.1921881117

E. coliexperimental assay

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