Dynamic plasticity within the EMT spectrum, rather than static mesenchymal traits, drives tumor heterogeneity and metastatic progression of breast cancers
M. S. Brown, B. Abdollahi, O. M. Wilkins, P. Chakraborty, N. B. Ognjenovic, K. E. Muller, M. K. Jolly, S. Hassanpour, D. R. Pattabiraman
This study identifies intermediate EMT states in breast cancer and develops a model to quantify their role in tumor heterogeneity and metastasis.
bioRxiv · Mar 17, 2021Cancer Biology