Mfn2 requires Hinge 1 integrity for efficient nucleotide-dependent assembly and membrane fusion
N. B. Samanas, E. A. Engelhart, S. Hoppins
The paper investigates the role of Hinge 1 in Mfn2's nucleotide-dependent assembly and membrane fusion, showing that variants with substitutions in this region exhibit fusion deficiencies and reduced assembly.
bioRxiv · Aug 19, 2019Cell Biology