A well conserved archaeal B-family polymerase functions as a mismatch and lesion extender
X. Feng, B. Zhang, Z. Gao, R. Xu, X. Liu, S. Ishino, M. Feng, Y. Shen, Y. Ishino, Q. She
The paper characterizes Sulfolobus islandicus DNA polymerase 2 (Dpo2), showing it extends mismatches and lesions but lacks 3-5 exonuclease activity, suggesting a role in DNA repair.
bioRxiv · Sep 10, 2021 · PreprintMicrobiology