Auranofin resistance in Toxoplasma gondii decreases the accumulation of reactive oxygen species but does not target parasite thioredoxin reductase
C. I. Ma, J. A. Tirtorahardjo, S. Jan, S. S. Schweizer, S. A. C. Rosario, Y. Du, J. J. Zhang, N. S. Morrissette, R. M. Andrade
This study identifies auranofin resistance mechanisms in Toxoplasma gondii, showing reduced ROS accumulation without targeting thioredoxin reductase.
Frontiers in Cellular and Infection Microbiology · Mar 19, 2021Peer-reviewedMicrobiology