Single cell spatial transcriptomic profiling of childhood-onset lupus nephritis reveals complex interactions between kidney stroma and infiltrating immune cells.
P. Danaher, N. Hasle, E. Nguyen, K. Hayward, N. Rosenwasser, C. E. Alpers, R. C. Reed, D. Okamura, S. K. Baxter, S. W. Jackson
This study uses single cell spatial transcriptomics to analyze kidney tissue from childhood-onset lupus nephritis patients, revealing spatial interactions between immune cells and kidney stroma.
bioRxiv · Nov 9, 2023 · PreprintImmunology