AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis
S. K. McRee, A. L. Bayer, J. Pietruska, P. Tsichlis, P. W. Hinds
This study shows AKT2 promotes melanoma metastasis while AKT1 is critical for tumor initiation, suggesting AKT2 as a therapeutic target in BRAF-mutant melanoma.
bioRxiv · Aug 24, 2023 · PreprintCancer Biology