Inhibiting the copper efflux system in microbes as a novel approach for developing antibiotics
A. Meir, V. Lepechkin-Zilbermintz, S. Kahremany, F. Schwerdtfeger, L. Gevorkyan-Airapetov, A. Munder, O. Viskind, A. Gruzman, S. Ruthstein
This study develops peptide inhibitors targeting the bacterial copper efflux system CusCFBA to combat antibiotic resistance by exploiting copper toxicity.
bioRxiv · Sep 9, 2019Biochemistry