S. Kannoly

A single-cell approach reveals variation in cellular phage-producing capacities

This study estimates single-cell bacteriophage lambda burst sizes and shows that burst size variation is due to cellular production capacity rather than lysis timing noise.

An optimal lysis time maximizes bacteriophage fitness in quasi-continuous culture

The paper tests an optimality model for bacteriophage lysis time in quasi-continuous culture and finds that productivity is maximized at 63 minutes, matching the wildtype strain's lysis time.

Optimum Threshold Minimizes Noise in Timing of Intracellular Events

The paper studies how noise in holin expression affects lysis timing in E. coli infected by bacteriophage λ, finding that noise decreases to a minimum and then increases with lysis time.