Anomalous reverse transcription through chemical modifications in polyadenosine stretches
W. Kladwang, V. V. Topkar, B. Liu, T. Hodges, S. Keane, H. Al-Hashimi, R. Das
The paper re-analyzes data on reverse transcriptase behavior at chemically modified polyadenosine stretches, finding near-quantitative bypass of modifications.
bioRxiv · Jan 7, 2020Biochemistry