THE ASSOCIATION OF CD47 WITH INTEGRIN Mac-1 REGULATES MACROPHAGE RESPONSES BY STABILIZING THE EXTENDED INTEGRIN CONFORMATION
N. P. Podolnikova, S. Key, X. Wang, T. P. Ugarova
This study shows CD47 stabilizes the extended conformation of Mac-1 integrin, enhancing macrophage functions like adhesion and phagocytosis.
bioRxiv · Sep 30, 2022 · PreprintCell Biology