Drug-target binding quantitatively predicts optimal antibiotic dose levels
F. Clarelli, A. Palmer, B. Singh, M. Storflor, S. Lauksund, T. Cohen, S. Abel, P. Abel zur Wiesch
This paper develops a computational model to predict antibiotic dose-response relationships from drug-target binding parameters and validates it with clinical isolates.
bioRxiv · Jun 27, 2019Biochemistry