Evaluating the role of inhibiting the biosynthesis of estrogens in the sex-specific antidepressant-like effects of ketamine in rats
S. Ledesma-Corvi, J. Jornet-Plaza, M. J. Garcia-Fuster
This study investigates how inhibiting estrogen biosynthesis with letrozole affects ketamine's antidepressant-like effects in male and female rats, showing sex-specific outcomes.
bioRxiv · Mar 29, 2023 · PreprintPharmacology & Toxicology