PD-1 Mediated Regulation of Unique Activated CD8+ T Cells by NK Cells in the Submandibular Gland
L. Brossay, S. M. Borys, S. P. Reilly, I. Magill, D. Zemmour
The paper identifies PD-1 deficiency in mice leads to increased CD8+ T cells in the submandibular gland, resembling immune-related adverse events, and shows NK cells regulate these cells via the PD-1/PD-L1 axis.
bioRxiv · Sep 15, 2023Immunology