Resolving the Interactions Between Class 3 Semaphorin Receptors in Live Cells
S. M. Christie, J. Hao, E. Tracy, M. Buck, J. S. Yu, A. W. Smith
This study uses PIE-FCCS to analyze receptor interactions in live cells, finding that Plexin D1 is monomeric while others form dimers or heteromers, with ligand-induced complex formation only observed for Plexin D1 and neuropilin-1.
bioRxiv · Feb 18, 2021 · PreprintBiophysics