BiophysicsbioRxivPreprint
Mechanistic modeling of amyloid oligomer and protofibril formation
K. Yuzu, H. Imamura, T. Nozaki…·E. Chatani
This study establishes a mechanistic model of amyloid oligomer and protofibril formation in bovine insulin using light scattering and kinetic analysis, revealing end-to-end association as the rate-limiting step.
DOI 10.1101/2023.09.02.556028