Author

S. Masscheleyn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

B. Miroux· 2 shared F. Bouillaud· 2 shared M. Piel· 2 shared A. Gagelin· 1 shared C. Largeau· 1 shared D. Calderon-Mora· 1 shared J. Henin· 1 shared K. Moncoq· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

B. Miroux

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2 papers

Recent·Most cited

Molecular determinants of inhibition of UCP1-mediated respiratory uncoupling

A. Gagelin, C. Largeau, S. Masscheleyn, M. Piel, D. Calderon-Mora, F. Bouillaud, J. Henin, B. Miroux

This study identifies molecular mechanisms by which purine nucleotides inhibit UCP1-mediated respiratory uncoupling using simulations and mutagenesis.

bioRxiv · Dec 9, 2022 · PreprintBiophysics

Structural models of mitochondrial uncoupling proteins obtained in DPC micelles are not physiologically relevant for their uncoupling activity.

M. Piel, S. Masscheleyn, F. Bouillaud, K. Moncoq, B. MIROUX

The paper shows that UCP1 mutants identified through NMR in DPC detergent do not affect activation in a yeast mitochondrial assay, suggesting DPC-based models are not physiologically relevant.

bioRxiv · Jul 20, 2020Biochemistry