How persistent infection overcomes peripheral tolerance mechanisms to cause T cell-mediated autoimmune disease
R. Yin, S. Melton, E. Huseby, M. Kardar, A. K. Chakraborty
The paper shows that persistent infections increase the likelihood of autoimmune T cell activation by exceeding a quorum threshold through molecular mimicry.
bioRxiv · Sep 13, 2023 · PreprintImmunology