Interplay between nucleoid-associated proteins and transcription factors in controlling specialized metabolism in Streptomyces
X. Zhang, S. N. Andres, M. A. Elliot
This study investigates how Lsr2 represses and CmlR activates the chloramphenicol biosynthetic cluster in Streptomyces venezuelae, revealing their opposing roles in regulating antibiotic production.
bioRxiv · Apr 15, 2021Microbiology