Author

M. A. Elliot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:gene regulatory network inference· 4 Research Focus:development & morphogenesis· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

X. Zhang· 2 shared A. R. Johnson· 1 shared C. A. Rees· 1 shared E. E. Carlson· 1 shared E. J. Gehrke· 1 shared E. M. F. Shepherdson· 1 shared E. M. Shepherdson· 1 shared H. Hindra· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

X. Zhang

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6 papers

Recent·Most cited

A complex regulatory network governs the production of an antibiotic with unusual cell-density-dependence

H. Hindra, M. A. Elliot

This paper identifies a complex regulatory network controlling density-dependent saquayamycin production in Streptomyces, involving Lsr2, PhoRP, and other regulators.

bioRxiv · Dec 13, 2023Microbiology

Redefining development in Streptomyces bacteria: integrating exploration into the classical sporulating life cycle

E. M. Shepherdson, M. A. Elliot

This paper shows that Streptomyces bacteria can perform exploratory growth and sporulation simultaneously in response to nutritional cues, with shared genetic requirements and distinct environmental impacts.

bioRxiv · Aug 23, 2023 · PreprintMicrobiology

Exploratory growth in Streptomyces venezuelae involves a unique transcriptional program, enhanced oxidative stress response, and profound acceleration in response to glycerol

E. M. F. Shepherdson, T. Netzker, Y. Stoyanov, M. A. Elliot

bioRxiv · Dec 22, 2021Microbiology

Interplay between nucleoid-associated proteins and transcription factors in controlling specialized metabolism in Streptomyces

X. Zhang, S. N. Andres, M. A. Elliot

This study investigates how Lsr2 represses and CmlR activates the chloramphenicol biosynthetic cluster in Streptomyces venezuelae, revealing their opposing roles in regulating antibiotic production.

bioRxiv · Apr 15, 2021Microbiology

Specialized and shared functions of diguanylate cyclases and phosphodiesterases in Streptomyces development.

J. Haist, S. A. Neumann, M. M. Al-Bassam, S. Lindenberg, M. A. Elliot, N. Tschowri

This study investigates the roles of c-di-GMP enzymes in Streptomyces development, revealing their specialized and shared functions in regulating sporulation and gene expression.

Molecular Microbiology · Aug 14, 2020Peer-reviewedMicrobiology

Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2

E. J. Gehrke, X. Zhang, S. M. Pimentel-Elardo, A. R. Johnson, C. A. Rees, S. E. Jones, Hindra, S. S. Gehrke, S. Turvey, S. Boursalie, J. E. Hill, E. E. Carlson, J. R. Nodwell, M. A. Elliot

This study shows that Lsr2 represses specialized metabolic gene clusters in Streptomyces, revealing its role in silencing cryptic metabolism and controlling the production of secondary metabolites.

bioRxiv · Apr 22, 2019Microbiology