Author

S. N. Krylov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:flow cytometry· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

V. Koshkin· 3 shared C. Peng· 2 shared M. Bleker de Oliveira· 2 shared A. Covens· 1 shared C. G. R. Perry· 1 shared G. Liu· 1 shared L. E. Ailles· 1 shared M. Bleker de Oliveria· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

V. Koshkin

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Author profile →

3 papers

Recent·Most cited

Assessment of Heterogeneity of Cytochrome P450 Activity in Cancer-Cell Population by Cytometry of Reaction Rate Constant is Robust to Variation in Substrate Concentration

M. Bleker de Oliveira, V. Koshkin, C. G. R. Perry, S. N. Krylov

This study demonstrates that CRRC is robust to substrate concentration variation when assessing CYP activity heterogeneity in cancer cells.

bioRxiv · Oct 15, 2020 · PreprintCancer Biology

Sequential Measurements of Catalytic Activities of Multi-Drug-Resistance Transporters and Cytochrome P450 Enzymes by Cytometry of Reaction Rate Constant

V. Koshkin, M. Bleker de Oliveria, S. Kochmann, C. Peng, S. N. Krylov

This study compares sequential measurements of MDR transporter and CYP enzyme activities using CRRC to determine if the order affects results, finding that MDR activity is significantly impacted by prior CYP measurement.

bioRxiv · Oct 15, 2020 · PreprintCancer Biology

Multi-Drug-Resistance in Drug-Naive and Drug-Exposed Ovarian Cancer Cells Responds Differently to Cell Culture Dimensionality

V. Koshkin, M. Bleker de Oliveira, C. Peng, L. E. Ailles, G. Liu, A. Covens, S. N. Krylov

The paper examines how cell clustering affects intrinsic and acquired multi-drug resistance in ovarian cancer cells using cytometry of reaction rate constants.

bioRxiv · Jul 12, 2020Cancer Biology