Author

S. Nelson-Sathi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Assay:proteomics· 3 Organism:bacteria (other)· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:metagenomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

S. R. C. Nori· 3 shared W. F. Martin· 3 shared J. John· 2 shared N. Kapust· 2 shared S. B. Gould· 2 shared S. G. Garg· 2 shared A. G. Tielens· 1 shared A. Jaya Ganesh· 1 shared

Activity by Year

2018-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersEvolutionary Biology

S. R. C. Nori

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Mutational landscape and in silico structure models of SARS-CoV-2 Spike Receptor Binding Domain reveal key molecular determinants for virus-host interaction

S. Nelson-Sathi, P. K. Umasankar, S. Easwaran, R. R. Nair, I. Joseph, S. R. C. Nori, J. S. Philip, R. Prasad, K. V. Navyasree, S. Ramesh, H. Pillai, S. Gosh, S. K. TR, M. R. Pillai

The paper analyzes mutations in SARS-CoV-2 Spike RBD across 31,403 genomes, identifies key molecular determinants for RBD-ACE2 binding, and proposes implications for vaccine and therapeutic design.

bioRxiv · May 2, 2020Evolutionary Biology

Evolutionary route of resistant genes in Staphylococcus aureus

J. John, S. George, S. R. C. Nori, S. Nelson-Sathi

This study identifies the evolutionary routes of resistant genes in S. aureus through phylogenomic analysis, revealing frequent lateral gene transfer from non-Staphylococcus sources.

bioRxiv · Sep 9, 2019Evolutionary Biology

Anomalous phylogenetic behavior of ribosomal proteins in metagenome assembled genomes

S. G. Garg, N. Kapust, W. Lin, S. Nelson-Sathi, F. D. K. Tria, S. B. Gould, L. Fan, R. Zhu, C. Zhang, W. F. Martin

The paper shows that Asgard and CPR metagenome assembled genomes (MAGs) fail to meet basic phylogenetic criteria due to their anomalous ribosomal protein evolutionary histories, suggesting they are binning artifacts.

bioRxiv · Aug 9, 2019 · PreprintEvolutionary Biology

Insights into the bacterial profiles and resistome structures following severe 2018 flood in Kerala, South India

S. Jaya Divakaran, J. Sara Philip, P. Chereddy, S. R. C. Nori, A. Jaya Ganesh, J. John, S. Nelson-Sathi

This study examines bacterial profiles and resistome structures in Kerala, India after a severe 2018 flood, finding altered microbial communities and increased antibiotic resistance.

bioRxiv · Jul 5, 2019Microbiology

Adaptation to life on land at 21% O2 via transition from ferredoxin- to NADH-dependent redox balance

S. B. Gould, S. G. Garg, M. Handrich, S. Nelson-Sathi, N. Gruenheit, A. G. Tielens, W. F. Martin

The paper shows algae maintain anaerobic metabolism enzymes at 21% O2, while land plants and animals shifted to NADH-based redox balance during terrestrialization.

bioRxiv · Jun 24, 2019Evolutionary Biology

Count does not recover major events of gene flux in real biological data

N. Kapust, S. Nelson-Sathi, B. Schoenfeld, E. Hazkani-Covo, D. Bryant, P. J. Lockhart, M. Roettger, J. C. Xavier, W. F. Martin

The paper tests Count's ability to detect mass gene transfer events and finds it biases towards uniform distribution rather than sporadic acquisition and differential loss.

bioRxiv · Jan 10, 2018Evolutionary Biology