Mutational landscape and in silico structure models of SARS-CoV-2 Spike Receptor Binding Domain reveal key molecular determinants for virus-host interaction
S. Nelson-Sathi, P. K. Umasankar, S. Easwaran…·M. R. Pillai
The paper analyzes mutations in SARS-CoV-2 Spike RBD across 31,403 genomes, identifies key molecular determinants for RBD-ACE2 binding, and proposes implications for vaccine and therapeutic design.