Author

S. Pääbo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

J. Kelso· 2 shared P. Khaitovich· 2 shared A. Vanyushkina· 1 shared B. M. Peter· 1 shared B. Vernot· 1 shared C. Conrad· 1 shared C. Schneider· 1 shared D. Macak· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersEvolutionary Biology

J. Kelso

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4 papers

Recent·Most cited

Evolutionary BiologybioRxivNov 29, 2021

The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals

S. Peyregne, J. Kelso, B. M. Peter, S. Pääbo

The paper traces the evolutionary history of human spindle genes, revealing gene flow between modern humans and Neandertals, with some variants present in Neandertals and inherited by non-Africans.

DOI 10.7554/elife.75464

humannon-human primate

𝕏 PostBluesky

Evolutionary BiologybioRxivNov 8, 2021

The molecular evolution of spermatogenesis across mammals

F. Murat, N. Mbengue, S. B. Winge…·H. Kaessmann

This study analyzes single-nucleus transcriptomes from testes across eleven mammalian species to uncover molecular evolution patterns in spermatogenesis.

DOI 10.1038/s41586-022-05547-7

mousehuman

𝕏 PostBluesky

Evolutionary BiologybioRxivMay 11, 2020

Reduced purine biosynthesis in humans after their divergence from Neandertals

V. Stepanova, K. E. Moczulska, G. N. Vacano…·S. Pääbo

The paper compares metabolomes across humans, chimpanzees, and macaques to identify reduced purine biosynthesis in humans, linked to an amino acid substitution in adenylosuccinate lyase.

DOI 10.7554/elife.58741

humanchicken / avian

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Evolutionary BiologybioRxivJul 4, 2018

The limits of long-term selection against Neandertal introgression

M. Petr, S. Pääbo, J. Kelso, B. Vernot

The paper shows that apparent declines in Neandertal ancestry in modern humans are artifacts, not evidence of negative selection, and finds no long-term decline in Neandertal ancestry over 45,000 years.

DOI 10.1073/pnas.1814338116

humanwhole-genome sequencing

𝕏 PostBluesky