Macrophage-specific NF-kappa B activation dynamics can segregate inflammatory bowel disease patients
S. Papoutsopoulou, M. D. Burkitt, F. Bergey, H. England, R. Hough, L. Schmidt, D. G. Spiller, M. H. White, P. Paszek, D. A. Jackson, V. A. Martins Dos Santos, G. Sellge, D. M. Pritchard, B. J. Campbell, W. Muller, C. Probert
This paper uses dynamic NF-kappaB activation assays in macrophages to stratify IBD patients into distinct phenotypic groups based on their response to stimulation.
bioRxiv · Jan 30, 2019Immunology