Episodic pain in Fabry disease is mediated by a heat shock protein-TRPA1 axis.
Jonathan David Enders, Eve K. Prodoehl, S. Penn, Anvitha Sriram, Cheryl L. Stucky
This study establishes a heat-induced pain model in Fabry disease and identifies a heat shock protein-TRPA1 regulatory axis as a key mechanism.
bioRxiv · Feb 20, 2025 · PreprintNeuroscience