The interplay between oxidative stress and inflammation supports autistic-related behaviors in mice
L. Pangrazzi, E. Cerilli, L. Balasco, C. Tobia, G. M. Dall'O', G. Chelini, S. Perini, M. Filosi, T. Ravizza, A. Vezzani, G. Provenzano, A. Pastore, B. Weinberger, E. Domenici, Y. Bozzi
This study shows that oxidative stress and inflammation interact to support autistic-like behaviors in Cntnap2-deficient mice, with NAC treatment improving these behaviors and microglia function.
bioRxiv · Sep 11, 2023 · PreprintImmunology