Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability and resistance to fibrinolysis
H. McPherson, C. Duval, S. R. Baker, M. S. Hindle, L. T. Cheah, N. L. Asquith, M. M. Domingues, V. C. Ridger, S. D. A. Connell, K. Naseem, H. Philippou, R. A. Ajjan, R. Ariens
This study investigates the role of fibrinogen αC-subregions in clot structure, mechanical stability, and resistance to lysis using recombinant variants.
bioRxiv · May 7, 2021Physiology