Genome-Wide Asymptomatic B-Cell, CD4+ and CD8+ T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines
S. Prakash, S. Ruchi, P.-G. Coulon, N. R. Dhanushkodi, A. A. Chentoufi, D. F. Tifrea, R. A. Edwards, C. J. Figueroa, S. D. Schubl, L. Hsieh, M. J. Buchmeier, M. Bouziane, A. B. Nesburn, B. D. Kuppermann, L. BenMohamed
The paper identifies conserved B-cell and T-cell epitopes across multiple Coronaviruses to inform the development of a pan-Coronavirus vaccine.
bioRxiv · Sep 27, 2020Immunology