Author

S. S. Neti

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Biophysics· 1

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Approach:deep learning· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

E. P. O'Brien· 1 shared I. Sitarik· 1 shared P. Pradhan· 1 shared P. To· 1 shared S. D. Fried· 1 shared S. J. Booker· 1 shared Y. Jiang· 1 shared Y. Xia· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

E. P. O'Brien

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1 paper

Recent·Most cited

How synonymous mutations alter enzyme structure andfunction over long time scales

Y. Jiang, S. S. Neti, I. Sitarik, P. Pradhan, P. To, Y. Xia, S. D. Fried, S. J. Booker, E. P. O'Brien

This paper shows that synonymous mutations alter enzyme function over time by causing misfolded, entangled protein states that reduce catalytic activity.

bioRxiv · Aug 18, 2021 · PreprintBiophysics